• ryedaft@sh.itjust.works
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    5 个月前

    Does it elicit a psychoactive reaction or does it affect TRPV3 in vitro?

    be honest David Beckham meme

    • fullsquare
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      5 个月前

      is TRPV3 even involved in any way because last time i’ve checked some of best evidence points in direction of TrkB

  • jaybone@lemmy.zip
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    5 个月前

    I want to see someone correct that commentor by telling them frankincense was the name of the doctor not the monster.

  • yuri@pawb.social
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    5 个月前

    incensole acetate has ~1/10th the anti-anxiety potency of valium, which is pretty darn high if you think about it!

    myrrh is also psychoactive, but it’s a straight up opoid agonist. it was commonly used as a pain reliever before the widespread use of opium poppies. in high-ish concentrations folks report general euphorua, dream-like states, and even vivid/lucid dreams! i can personally attest to the first two hahah

  • TankovayaDiviziya@lemmy.world
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    5 个月前

    Religion itself is said to be natural antidepressant. I do wonder if exposure by our ancestors to psychoactive substances is tied to the development of religion.

    • ssillyssadass@lemmy.world
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      5 个月前

      I figured it was traditionally used because it’s what was given to baby JC by the three wise men, so it’s considered holy in a sense

        • Evil_Shrubbery@lemmy.zip
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          5 个月前

          Bcs the market speculation predicted that after prob 1k years it will enter the mass use by a major religion & could be sold at a higher price then, duh.

          /s

    • Corkyskog@sh.itjust.works
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      5 个月前

      Probably shouldn’t experiment with large doses of barely understood substances… But if someone really wanted to.

      You can buy Incensole Acetate from chemical companies, but it’s like hundred dollars for a few milligrams. Would have been cool for it to be cheap this form because you could probably use it in a passive nasal inhaler device at that strength.

      However you can buy 4oz of frankincense resin for ~$30. I would imagine that will have much more of Incensole than a few mg. No idea if it would be easy to inhale in vapor form or if you would have to burn it.

      No idea how reputable these sites selling it are, but here is one.

        • Corkyskog@sh.itjust.works
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          5 个月前

          Yeah, but they weren’t inhaling an isolate. It’s all about the dose.

          Edit: I misread your comment. I don’t know why there isn’t more research into the pathways frankincense uses to generate its effects. Probably because it’s rarely been used in a directly applied medical way instead of a communal or ceremonial use.

  • SkyHeart@lemmy.zip
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    5 个月前

    I actually got my hands on Frankincense drops and started to eat them like crazy, when I decided to try one of them. It tasted like actual raw glass like rocks although I liked eating them and didn’t knew why until now. Although they have almost zero to non taste, eating them was quite addictive in my experience

  • vaultdweller013@sh.itjust.works
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    5 个月前

    I’ll stick with my family trait that means when we fight we get happy brain juice, I just wish boxing or MMA could trigger it but it doesn’t. If the fight can’t theoretically end with me getting gutted with a rusty knife I want nothing to do with it, I want to Cain someone’s Able.